Martin-Luther-Universität Halle-Wittenberg

membrane-bound protein structure


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Dr. Christian Schwieger


24. Arabi SH, Aghelnejad B, Schwieger C, Meister A, Kerth A,Hinderberger  D (2018) Serum Albumin Hydrogels in Broad pH and Temperature Ranges:  Characterization of Their Self-Assembled Structures, Nanoscopic and Macroscopic Properties.
Biomaterial Science
, DOI: 10.1039/C7BM00820A   

2015 - 2017

23. Schwieger C*, Meister A, Daum S, Blume A, Bacia K* (2017)
Binding of the GTPase Sar1 to a Lipid Membrane Monolayer: Insertion and Orientation studied by Infrared-Reflection-Absorption Spectroscopy.
Polymers, 9, 612, DOI: 10.3390/polym9110612   

22. Shah SWH, Schwieger C, Li Z, Kressler J, Blume A (2017)
Effect of Perfluoroalkyl Endgroups on the Interactions of Tri-block Copolymers with Monofluorinated F-DPPC Monolayers.
Polymers, 9, 555, DOI: 10.3390/polym9110555   

21. Hädicke A, Schwieger C, Blume A (2017)
Co-spreading of  anionic phospholipids with peptides of the structure (KX)4K at the air-water interface: Influence of lipid headgroup structure and hydrophobicity of the peptide on monolayer behavior.
Langmuir, 33, 12204–17, DOI: 10.1021/acs.langmuir.7b02255   

20. Reichenwallner J, Schwieger C, Hinderberger D (2017)
Probing the Nanoscopic Thermodynamic Fingerprint of Paramagnetic Ligands Interacting with Amphiphilic Macromolecules
Polymers, 9, 324, DOI: 10.3390/polym9080324   

19. Jbeily M, Schwieger C, Kressler J (2017)
Mixed  Langmuir monolayers of perfluorostearic acid and stearic acid studied by epifluorescence microscopy using fluorinated rhodamines and infrared reflection absorption spectroscopy (IRRAS)
Colloids and Surfaces A, 529(C), 274-85,
DOI: 10.1016/j.colsurfa.2017.06.004   

18. Schwieger C, Liu X, Krafft MP (2017)
Self-assembled mesoscopic surface domains of fluorocarbon-hydrocarbon diblocks can form at zero surface pressure. Tilting of solid-like hydrocarbon moieties compensates for cross-section mismatch with fluorocarbon moieties
Physical Chemistry Chemical Physics, 19, 23809-16
DOI: 10.1039/C7CP02432K   

17. Hoernke M, Mohan J, Larsson E, Blomberg J, Kahra D, Westenhoff S, Schwieger C* and Lundmark R* (2017)
EHD2 restrains dynamics of caveolae by an ATP-dependent, membrane-bound, open conformation
PNAS, 214 (22), E4360-96, DOI: 1073/pnas.1614066114   

16. Schwieger C*, Blaffert J, Li Zheng, Kressler J, Blume A (2016)
Perfluorinated Moieties Increase the Interaction of Amphiphilic Block Copolymers with Lipid Monolayers
Langmuir, 32(32), 8102-8115, DOI: 10.1021/acs.langmuir.6b01574   

15. Fuchs C, Hussain H, Schwieger C, Schulz M, Binder M, Kressler J (2015) Molecular Arrangement of Symmetric and Non-symmetric Triblock Copolymers of Poly(ethylene oxide) and Poly(isobutylene) at the Air/Water Interface
Journal of Colloid and Interface Science,
437, 80-89,
DOI: 10.1016/j.jcis.2014.09.050   

2010 - 2014

14. Schwieger C*, Achilles A, Scholz S, Rüger J, Bacia K, Saalwaechter K, Kressler J, Blume A (2014)
Binding of Amphiphilic and Triphilic Block Copolymers to Lipid Model Membranes: The Role of Perfluorinated Moieties
Soft Matter, 10, 6147-60
DOI: 10.1039/c4sm00830h   

13. Rabe M, Schwieger C, Zope HR, Versluis F, Kros A* (2014)
Interactions of Fusogenic Coiled-Coil Lipopeptides with Zwitterionic Lipid Monolayers: Implications for Lipopeptide Mediated Vesicle Fusion
Langmuir, 30, 7727-35
DOI: 10.1021/la500987c   

12. Finger S, Schwieger C,  Arouri A, Kerth A, Blume A* (2014)
Interaction of linear polyamines with negatively charged phospholipids: The effect of polyamine charge distance
Biological Chemistry
395, 769-78
DOI: 10.1515/hsz-2014-0126   

11.  Menzel A, Neumann P, Schwieger C, Stubbs M* (2014) Thermodynamic  signatures in macromolecular interactions involving conformational  flexibility
Biological Chemistry 395, 905-11
DOI: 10.1515/hsz-2014-0177   

10. Schrettel S, Stefaniu C, Schwieger C, ... Frauenrath H* (2014)
Functional Carbon Nanosheets Prepared from Hexayne Amphiphile Monolayers at Room Temperature
Nature Chemistry 6, 468–476
DOI: 10.1038/NCHEM.1939   

9. Schwieger C, Ropers MH* (2013)
Binding of a perfluorinated surfactant to beta-Lactoglobulin in aqueous solution
Food Hydrocolloids 30, 241-8
Doi: 10.1016/j.foodhyd.2012.05.021   

8. Schwieger C*, Chen B, Tschierske C, Kressler J, Blume A (2012)
Structure of Self-Organized Films of T-Shaped Facial Amphiphiles at the Air/Water Interface Studied by Infrared-Reflection-Absorption-Spectroscopy
Journal of Physical Chemistry B 116 (40), 12245 – 56
Doi: 10.   1021/jp306612k   

7. Hoernke M, Schwieger C, Kerth A, Blume A* (2012)
Binding  of cationic pentapeptides with modified side chain lengths to  negatively charged lipid membranes: Complex Interplay of Electrostatic  and Hydrophobic Interactions.
BBA - Biomembranes 1818, 1663 - 72
DOI: 10.1016/j.bbamem.2012.03.001   

6. Hoernke M, Falenski JA, Schwieger C, Koksch B, Brezesinski G* (2011)
Triggers for b-Sheet Formation at the Hydrophobic-Hydrophilic Interface: High Concentration, In-Plane Orientational Order, and Metal Ion Complexation. Langmuir 27(23), 14218 - 31

5. Kyeremateng SO, Schwieger C, Blume A, Kressler J* (2010)
Triphilic Block Copolymers: Synthesis, Aggregation Behaviour and Interactions with Phospholipid Membranes.ACS Books: "Contemporary Science of Polymeric Materials" Vol. 1016, 5, 65-84
Doi: 10.1021/bk-2010-1061.ch005   

2007 - 2009

4. Schwieger C, Blume A* (2009)
Interaction of Poly(L-arginine) with Negatively Charged DPPG Membranes: Calorimetric and Monolayer Studies.
Biomacromolecules 10, 2152-61
DOI: 10.1021/bm9003207   

3. Reuter M, Schwieger C, Meister A, Karlsson G, Blume A* (2009)
Poly-L-lysines and poly-L-arginines induce leakage of negatively charged phospholipid vesicles and translocate through the lipid bilayer upon electrostatic binding to the membrane.
Biophys Chem 144, 27-37
DOI: 10.1016/j.bpc.2009.06.002   

2. Förster G, Schwieger C, Faber F, Weber T, Blume A* (2007)
Influence of poly(l-lysine) on the structure of dipalmitoylphosphatidylglycerol/water dispersions studied by X-ray scattering.
Eur Biophys J 36, 425-35
DOI: 10.1007/s00249-006-0087-1   

1. Schwieger C, Blume A* (2007)
Interaction of poly(L-lysines) with negatively charged membranes: an FT-IR and DSC study.
Eur Biophys J 36, 437-50
DOI: 10.1007/s00249-006-0080-8    


Conformational change upon protein binding to lipid membrane (BPS 2016)
BPS2016_Hoernke_Schwieger.pdf (nur intern abrufbar) (2,1 MB)  vom 30.05.2016

SNARE mimetics: membrane interactions of fusogenic peptides (EBSA 2015)
Schwieger_EBSA_2015_SNAREpeptides_c.pdf (nur intern abrufbar) (externe Datei)

Triphilic Block Copolymers: The role of perfluorinated moities (Biomembrane Days 2014)
Schwieger_Biomembrane_Days_2014_final2.pdf (externe Datei)

IRRAS: Orientation of membrane bound Sar1p (Hühnfeld 2014)
Schwieger_Gomadingen_2014_c.pdf (nur intern abrufbar) (969,1 KB)  vom 25.07.2015

IRRAS: Amphiphilic liquid crystals (Gomadingen 2012)
Schwieger_Gomadingen_Poster.pdf (externe Datei)

Poly(L-Arginin) interacting with lipid membraens (EBSA 2011)
Poster_EBSA_Schwieger_PLA_AB2.pdf (externe Datei)

PLL and PLA bindung to membranes: Contribution of non-electrostatic interactions
Poster_York_2008_AB.pdf (externe Datei)

Whey proteins at the air/water interface (LB13 2010)
Poster_LB13_schwieger-ropers2_CS2.pdf (externe Datei)

Propeties of milk proteins upon interaction with perluorinated surfactants
Poster_ChristianSchwieger_ECIS_2009.pdf (externe Datei)

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