Martin-Luther-Universität Halle-Wittenberg

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Dr. Christian Schwieger

von-Dankelman-Platz 4, Raum 1.12
Phone: +49 (0)345 55 25858
Lab: E.07,  +49 (0)345 25824

Kurth-Mothes-Straße 3, Raum 100
Phone: +49 (0)345 22817

research interests

  • electrostatic interactions of positively charged peptides with lipid membranes
  • role of arginines for incorporation of peptides / proteins into lipid membranes
  • conformation of milk proteins at the air/water interface
  • influence of fluorinated surfactants on structure and function of milk proteins
  • self-organization of polyphilic molecules / polymers at the air/water interface
  • interaction of synthetic polyphilic molecules / polymers with lipid monolayers and vesicles
  • simulation of infrared reflection absorption spectra (IRRAS)
  • Conformational changes of membrane binding / shaping proteins
  • Fusogenic Lipo-peptides
  • influence of perfluorinated moieties on interactions of polyphilic polymers with lipid monolayers
  • Self-aggregation of semi-fluorinated alkanes at the air/water interface
  • stabilization of gas bubbles with PEGylated lipids for ultrasound application

methods

  • Infrared reflection absorption spectroscopy      (IRRAS)
  • ATR FTIR, Transmission FTIR, FTIR Microscopy
  • Monolayer techniques  (Film balance,      Brewster angle microscopy, Epi-fluorescence spectroscopy, GISAX, X-ray      reflectometry)
  • Calorimetry (DSC, ITC)
  • Fluorescence spectroscopy
  • Dynamic light scattering
  • X-ray diffraction

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