Publications
2023
Light‐Controlled Biocatalysis by Unspecific Peroxygenases with Genetically Encoded Photosensitizers, Pascal Püllmann, Dominik Homann, Tobias A. Karl, Burkhard König, Martin J. Weissenborn
Angewandte Chemie Volume 62, Issue 41
Computational-Aided Engineering of a Selective Unspecific Peroxygenase toward Enantiodivergent β-Ionone Hydroxylation, J Münch, J Soler, N Hünecke, D Homann, M Garcia-Borràs, Martin J Weissenborn
ACS Catalysis 13, 8963-8972
A Career in Catalysis: Bernhard Hauer , Bernd A Nebel, Michael Breuer, Andreas Schneider, Benjamin Aberle, Stephan C Hammer, Per-Olof Syrén, Martin J Weissenborn, Bettina M Nestl
ACS Catalysis 13, 8861-8889
2022
YfeX–a new platform for carbene transferase development with high intrinsic reactivity , Victor Sosa Alfaro, Sodiq O Waheed, Hannah Palomino, Anja Knorrscheidt, Martin Weissenborn, Christo Z Christov, Nicolai Lehnert
Chemistry–A European Journal 28 (65), e202201474
Valorization of small alkanes by biocatalytic oxyfunctionalization , Durga Mahor, Zhiqi Cong, Martin J Weissenborn, Frank Hollmann, Wuyuan Zhang
ChemSusChem 15 (9), e202101116
2021
Enzymatic Hydroxylations of sp3-Carbons , J Münch, P Püllmann, W Zhang, MJ Weissenborn
ACS Catalysis 11 (15), 9168-9203
Accessing chemo-and regioselective benzylic and aromatic oxidations by protein engineering of an unspecific peroxygenase , Anja Knorrscheidt, Jordi Soler, Nicole Hünecke, Pascal Püllmann, Marc Garcia-Borràs, Martin J Weissenborn
ACS catalysis 11 (12), 7327-7338
Improving the Heterologous Production of Fungal Peroxygenases through an Episomal Pichia pastoris Promoter and Signal Peptide Shuffling System , P Püllmann, MJ Weissenborn
ACS Synthetic Biology 10 (6), 1360-1372
A modular two yeast species secretion system for the production and preparative application of unspecific peroxygenases , Pascal Püllmann, Anja Knorrscheidt, Judith Münch, Paul R Palme, Wolfgang Hoehenwarter, Sylvestre Marillonnet, Miguel Alcalde, Bernhard Westermann, Martin J Weissenborn
Communications biology 4 (1), 562
Enzymatic degradation of synthetic polyisoprenes via surfactant-free polymer emulsification , VKB Adjedje, E Schell, YL Wolf, A Laub, MJ Weissenborn, WH Binder
Green Chemistry 23 (23), 9433-9438
Simultaneous screening of multiple substrates with an unspecific peroxygenase enabled modified alkane and alkene oxyfunctionalisations , Anja Knorrscheidt, Jordi Soler, Nicole Hünecke, Pascal Püllmann, Marc Garcia-Borràs, Martin J Weissenborn
Catalysis Science & Technology 11 (18), 6058-6064
2020
Identification of novel unspecific peroxygenase chimeras and unusual YfeX axial heme ligand by a versatile high-throughput GC-MS approach , Anja Knorrscheidt, Pascal Püllmann, Eugen Schell, Dominik Homann, Erik Freier, Martin J. Weissenborn
ChemCatChem
Iron‐porphyrin catalyzed carbene transfer reactions–an evolution from biomimetic catalysis towards chemistry‐inspired non‐natural reactivities of enzymes , MJ Weissenborn, RM Koenigs
ChemCatChem 12, 2171-2179
2019
Pilzliche Peroxygenasen: der Schlüssel zu CH-Hydroxylierungen und mehr? , P Püllmann, MJ Weissenborn
BIOspektrum 25, 572-574
Golden Mutagenesis: An efficient multi-site saturation mutagenesis approach by Golden Gate cloning with automated primer design , Pascal Puellmann, Chris Ulpinnis, Sylvestre Marillonnet, Ramona Gruetzner, Steffen Neumann, Martin J Weissenborn
Scientific Reports 9
Tryptamine synthesis by iron porphyrin catalyzed C− H functionalization of indoles with diazoacetonitrile , Katharina J Hock, Anja Knorrscheidt, Renè Hommelsheim, Junming Ho, Martin J Weissenborn, Rene M Koenigs
Angewandte Chemie International Edition 58 (11), 3630-3634
2018
Modulating proposed electron transfer pathways in P450BM3 led to improved activity and coupling efficiency , D Darimont, MJ Weissenborn, BA Nebel, B Hauer
Bioelectrochemistry 119, 119-123
2017
Tackling the numbers problem: Entwicklung nicht-nativer Enzymreaktionen , M Kammel, A Knorrscheidt, P Püllmann, MJ Weissenborn
BIOspektrum 23, 830-832
Development of a solid phase array assay for the screening of galactose oxidase activity and for fast identification of inhibitors , MJ Weissenborn, DP Debecker, S Golten, B Linclau, NJ Turner, SL Flitsch
Protein and peptide letters 24 (8), 742-746
2016
Structure‐Guided Redesign of CYP153AM.aq for the Improved Terminal Hydroxylation of Fatty Acids , Sara M Hoffmann, Hamid‐Reza Danesh‐Azari, Claudia Spandolf, Martin J Weissenborn, Gideon Grogan, Bernhard Hauer
ChemCatChem 8 (20), 3234-3239
Enhanced Ene‐Reductase Activity through Alteration of Artificial Nicotinamide Cofactor Substituents , SA Löw, IM Löw, MJ Weissenborn, B Hauer
ChemCatChem 8 (5), 911-915
Expanding an efficient, electrically driven and CNT-tagged P450 system into the third dimension: a nanowired CNT containing and enzyme stabilising 3D sol-gel electrode , Enrique C. Llaudet, Dominique Darimont, Ramona Samba, Ilona Matiychyn, Martin Stelzle, Martin J. Weissenborn, Bernhard Hauer
Redox Partner Interaction Sites in Cytochrome P450 Monooxygenases: In Silico Analysis and Experimental Validation , Gricman, L, MJ Weissenborn, SM Hoffmann, N Borlinghaus, B Hauer, J Pleiss
ChemistrySelect
Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s , Martin J Weissenborn, Sandra Notonier, Sarah-Luise Lang, Konrad B Otte, Susanne Herter, Nicholas J Turner, Sabine L Flitsch, Bernhard Hauer
Chemical Communications 52, 6158-6161
Enzyme- Catalysed Carbonyl Olefination by the E. coli Protein YfeX in Absence of Phosphines , Martin J. Weissenborn, Sebastian A. Löw, Niels Borlinghaus, Miriam Kuhn, Stefanie Kummer, Fabian Rami, Bernd Plietker
ChemCatChem
2015
Process Investigations on the One-Pot Synthesis of Rifamycin S Avoiding Chlorinated Solvents , SA Löw, B Nestl, MJ Weissenborn, F Zepeck, B Hauer
Organic Process Research & Development 19, 1544-1547
2014
Glycosylation Characterization of Human and Porcine Fibrinogen Proteins by Lectin- Binding Biophotonic Microarray Imaging , RV Olkhov, MJ Weissenborn, SL Flitsch, AM Shaw
Analytical chemistry 86 (1), 621-628
2013
Profiling glycosyltransferase activities by tritium imaging of glycan microarrays , Sonia Serna, Cornelis H Hokke, Martin Weissenborn, Sabine Flitsch, Manuel Martin‐Lomas, Niels‐Christian Reichardt
ChemBioChem 14 (7), 862-869
Enzymatic reactions on immobilised substrates , CJ Gray, MJ Weissenborn, CE Eyers, SL Flitsch
Chemical Society Reviews 42 (15), 6378-6405
2012
Crystal structure of a soluble form of human CD73 with ecto‐5′‐nucleotidase activity , Dominic PHM Heuts, Martin J Weissenborn, Rouslan V Olkhov, Andrew M Shaw, Jennet Gummadova, Colin Levy, Nigel S Scrutton
Chembiochem 13 (16), 2384-2391
Glycoarrays on Gold Surfaces , P Both, R Sardzik, M Weissenborn, A Green, J Voglmeir, S Flitsch
Cracking the Sugar Code by Navigating the Glycospace, 93-105
Formation of carbohydrate-functionalised polystyrene and glass slides and their analysis by MALDI-TOF MS , Martin J Weissenborn, Johannes W Wehner, Christopher J Gray, Robert Šardzík, Claire E Eyers, Thisbe K Lindhorst, Sabine L Flitsch
Beilstein Journal of Organic Chemistry 8 (1), 753-762
Chemoenzymatic Synthesis of O-Mannosylpeptides in Solution and on Solid Phase , Robert Sardzik, Anthony P Green, Nicolas Laurent, Peter Both, Carolina Fontana, Josef Voglmeir, Martin J Weissenborn, Rose Haddoub, Paola Grassi, Stuart M Haslam, Goran Widmalm, Sabine L Flitsch
Journal of the American Chemical Society 134 (10), 4521-4524
Dual purpose S-trityl-linkers for glycoarray fabrication on both polystyrene and gold , Johannes W Wehner, Martin J Weissenborn, Mirja Hartmann, Christopher J Gray, Robert Šardzík, Claire E Eyers, Sabine L Flitsch, Thisbe K Lindhorst
Organic & biomolecular chemistry 10 (44), 8919-8926
Oxo-ester mediated native chemical ligation on microarrays: an efficient and chemoselective coupling methodology , Martin J Weissenborn, Roberto Castangia, Johannes W Wehner, Robert Šardzík, Thisbe K Lindhorst, Sabine L Flitsch
Chemical Communications 48 (37), 4444-4446
2010
Enzymatic glycosylations on arrays , J Voglmeir, R Šardzík, MJ Weissenborn, SL Flitsch
Omics: a journal of integrative biology 14 (4), 437-444
Preparation of aminoethyl glycosides for glycoconjugation , R Šardzík, GT Noble, MJ Weissenborn, A Martin, SJ Webb, SL Flitsch
Beilstein journal of organic chemistry 6 (1), 699-703